HCAIX-IN-16 - CAS 2849348-38-3

HCAIX-IN-16 (Compound 12d), an inhibitor of hCA IX, exhibits inhibition constants (K i) of 190.0 nM for hCA IX and 187.9 nM for hCA XII. It can arrest the cell cycle in the G0-G1 and S phases and induce apoptosis in MDA-MB-468 breast cancer cells. Demonstrating broad-spectrum anticancer activity, hCAIX-IN-16 is a potential tool for cancer research [1].

Carbonic Anhydrase

Metabolism

2849307

C20H20N8O2S

436.49

-20°C

Ice Packs

Small Compound