HCAIX-IN-8 - CAS 2414633-40-0

HCAIX-IN-8 (compound 7i) is a highly potent and selective inhibitor of hCAIX with an IC50 value of 0.024 μM, and also inhibits CAII and CAVA with IC50 values of 1.99 μM and 1.10 μM, respectively. It exhibits anti-proliferative effects, low toxicity, reduces epithelial-to-mesenchymal transitions, promotes apoptosis, and inhibits cell migration and colonization potential [1].

Others, Carbonic Anhydrase

Others, Metabolism

2414593

C19H16N4O6

396.35

C(OC1=C(OC)C=C(/C=C/C(O)=O)C=C1)C2=CN(N=N2)C3=CC(N(=O)=O)=CC=C3

-20°C

Ice Packs

Small Compound