Hck-IN-1 - CAS 1473404-51-1

Hck-IN-1 is a selective Nef-dependent Hck inhibitor (IC50s: 2.8 μM and >20 μM for Nef:Hck complex and Hck) with antiretroviral activity. Hck-IN-1 is a direct and wide HIV-1 Nef antagonist with an IC50 of 100-300 nM for wild-type HIV-1 replication.

Src, Hck, HIV Protease

Tyrosine Kinase/Adaptors, Angiogenesis, Proteases/Proteasome, Microbiology/Virology

1473352

0.9907

C16H11ClN6O3S

402.81

NC(=S)n1nc(c(\N=N\c2cccc(Cl)c2)c1O)-c1ccc(cc1)[N+]([O-])=O

-20°C

Ice Packs

Small Compound