HCYP1B1-IN-2 - CAS 3043683-33-3

HCYP1B1-IN-2 (compound 3n) is a potent inhibitor of the human enzyme cytochrome P450 1B1 (hCYP1B1) . It exhibits strong anti-hCYP1B1 activity with an IC50 of 0.040 nM and can also block AhR transcriptional activity. hCYP1B1-IN-2 effectively inhibits hCYP1B1 through a mixed inhibition mode with a Ki value of 21.71 pM.

Cytochromes P450, Aryl Hydrocarbon Receptor

Immunology/Inflammation, Metabolism

3043647

C17H10BrN3O2

368.18

O=C1C=2C=CC=C3C(Br)=CC=C(C(=O)N1CC=4C=NC=NC4)C32

-20°C

Ice Packs

Small Compound