HDAC/HSP90-IN-3 - CAS 2700035-54-5

HDAC/HSP90-IN-3 is a selective and potent dual inhibitor of fungal Hsp90 (IC50: 0.83 μM) and HDAC (IC50: 0.91 μM), exhibiting antifungal effects against azole-resistant Candida albicans. HDAC/HSP90-IN-3 exhibits inhibitory effects on important virulence factors and is able to downregulate the resistance genes ERG11 and CDR1.

HSP, Others, Antifungal, HDAC

Chromatin/Epigenetic, Others, DNA Damage/DNA Repair, Microbiology/Virology, Metabolism, Cytoskeletal Signaling

2700035-54-5

C26H33N5O6

511.57

O=C1N(C(=NN1)C2=CC(C(C)C)=C(O)C=C2O)C3=CC=C(C(NCCCCCCCC(NO)=O)=O)C=C3

-20°C

Ice Packs

Small Compound