HDAC-IN-39 - CAS 2414046-33-4

HDAC-IN-39 is a potent inhibitor of HDAC and is able to act on HDAC1, HDAC2 and HDAC3 with IC50 values of 1.07 μM, 1.47 μM and 2.27 μM, respectively. HDAC-IN-39 induces cell cycle arrest in G2/M phase and also significantly inhibits microtubule polymerization. HDAC-IN-39 exhibits good anticancer effects on HDAC-IN-39 exhibited good anti-cancer effects on drug-resistant cancer cells.

HDAC, Microtubule Associated, Others, Apoptosis

Chromatin/Epigenetic, Others, DNA Damage/DNA Repair, Cytoskeletal Signaling, Apoptosis

2414046-33-4

C27H26N4O4S

502.58

N(S(=O)(=O)C1=CC=C(OC)C=C1)C2=C(NCC3=CC=C(C(NC4=C(N)C=CC=C4)=O)C=C3)C=CC=C2

-20°C

Ice Packs

Small Compound