HDAC-IN-42 - CAS 2454024-18-9

HDAC-IN-42 (compound 14f) is a highly potent and selective inhibitor of histone deacetylase (HDAC) enzymes, with IC50 values of 0.19 μM for HDAC1 and 4.98 μM for HDAC6. It exhibits significant anticancer properties, inhibiting cell proliferation, inducing apoptosis, and causing cell cycle arrest specifically at the G2/M phase [1].

Apoptosis, Others, HDAC

Others, DNA Damage/DNA Repair, Apoptosis, Chromatin/Epigenetic

2453997

C20H15NO7

381.34

C(OC1=CC(/C=C/C(NO)=O)=CC=C1)(=O)C2=CC=3C(OC2=O)=CC(OC)=CC3

-20°C

Ice Packs

Small Compound