HDAC-IN-87 - CAS 3039482-69-1

HDAC-IN-87 (Compound XII6) is a non-selective HDAC inhibitor with pIC50 values of 6.9 for HDAC4 and 5.8 for HDAC6. It exhibits fungicidal activity against P. sorghi and P. pachyrhizi. The acute oral LD50 in both male and female rats is greater than 500 mg/kg.

Antifungal, HDAC

Microbiology/Virology, DNA Damage/DNA Repair, Chromatin/Epigenetic

3039412

C13H7F5N4O2S

378.277

FC(F)C=1N=CN=C(OCC=2SC(=CC2)C3=NOC(=N3)C(F)(F)F)C1

-20°C

Ice Packs

Small Compound