HDAC1-IN-8 - CAS 3066143-73-2

HDAC1-IN-8 (compound 5c) is a potent and selective HDAC1 inhibitor, with IC50 values of 11.94 μM for HDAC1, 22.95 μM for HDAC6, and greater than 500 μM for HDAC8. It exhibits antiproliferative activity, induces cell cycle arrest in G1 and G2/M phases, and triggers autophagy (autophagy) . Additionally, HDAC1-IN-8 demonstrates anticancer properties and holds potential for lung cancer research.

Autophagy, HDAC

Chromatin/Epigenetic, DNA Damage/DNA Repair, Autophagy

3066068

C22H24N2O4

380.437

O=C(NO)CCCCCOC=1C=CC2=NC(=CC=C2C1)C3=CC=C(OC)C=C3

-20°C

Ice Packs

Small Compound