HDAC6/8/BRPF1-IN-1 - CAS 2484255-65-2

HDAC6/8/BRPF1-IN-1 is a dual inhibitor targeting HDAC6, HDAC8, and the bromodomain and PHD finger containing protein 1 (BRPF1) . It exhibits inhibitory activity against HDAC1, HDAC6, and HDAC8 with IC50 values of 797 nM, 344 nM, and 908 nM, respectively, and inhibits BRPF1 with a Kd value of 175.2 nM. This compound is utilized in cancer research [1].

HDAC, Others

Others, Chromatin/Epigenetic, DNA Damage/DNA Repair

2484188

C18H17N3O5S

387.41

CN1C=2C(=CC(NS(=O)(=O)C3=CC=C(C(NO)=O)C=C3)=CC2)C=C(C)C1=O

-20°C

Ice Packs

Small Compound