HDAC6-IN-10 - CAS 2408286-73-5

HDAC6-IN-10 is a potent and specific HDAC6 inhibitor, exhibiting an IC50 value of 0.73 nM. It demonstrates remarkable selectivity towards HDAC6, with a selectivity range of 144 to 10,941-fold over other HDAC isoforms. Furthermore, HDAC6-IN-10 exhibits notable anti-proliferative effects on multiple myeloma cells [1].

HDAC, Others, Microtubule Associated

DNA Damage/DNA Repair, Chromatin/Epigenetic, Cytoskeletal Signaling, Others

2408208

C21H20N4O4

392.41

C(C=1C=2C(NC1)=CC=CC2)[C@@H]3C(=O)N(CC4=CC=C(C(NO)=O)C=C4)CC(=O)N3

-20°C

Ice Packs

Small Compound