HDAC6-IN-43 - CAS 3037978-19-8

HDAC6-IN-43 (compound 26) is a potent inhibitor of HDACs. This compound effectively inhibits various HDACs, notably HDAC1, HDAC2, and HDAC6, with an IC50 of less than 150 nM, and demonstrates particularly high sensitivity to HDAC6 with an IC50 of 11 nM. HDAC6-IN-43 is utilized in the study of autosomal dominant polycystic kidney disease (ADPKD) .

HDAC

DNA Damage/DNA Repair, Chromatin/Epigenetic

3037951

C21H24N2O4S

400.49

O=C(NO)CCCCCCOC1=CC(=CC=C1OC)C2=NC=3C=CC=CC3S2

-20°C

Ice Packs

Small Compound