HDAC6-IN-5 - CAS 2413603-15-1

HDAC6-IN-5 (compound 11b) is a potent and BBB-penetrated inhibitor of HDAC6 (IC50 = 0.025 μM) that inhibits Aβ 1-42 self-aggregation and AChE with IC50 values of 3.0 and 0.72 μM, respectively. Additionally, HDAC6-IN-5 can enhance neurite outgrowth without significant neurotoxicity.

Others, Beta Amyloid, Cholinesterase (ChE), HDAC

DNA Damage/DNA Repair, Neuroscience, Chromatin/Epigenetic, Others

2413587

C20H14BrN3O2

408.25

N(C=1C2=C(N=C3C1C=CC=C3)C=CC(Br)=C2)C4=CC=C(C(NO)=O)C=C4

-20°C

Ice Packs

Small Compound