HDAC6-IN-6 - CAS 2413603-10-6

HDAC6-IN-6 (compound 6a) is a potent HDAC6 inhibitor with an IC50 value of 0.025 μM that can penetrate the BBB. It exhibits strong inhibitory activity against AChE and Aβ 1-42 self-aggregation with IC50 values of 0.72 and 3.0 μM, respectively. HDAC6-IN-6 also enhances neurite outgrowth without significant neurotoxicity [1].

Others, Beta Amyloid, Cholinesterase (ChE), HDAC

Others, Chromatin/Epigenetic, Neuroscience, DNA Damage/DNA Repair

2413587

C20H15N3O2

329.35

N(C=1C2=C(N=C3C1C=CC=C3)C=CC=C2)C4=CC=C(C(NO)=O)C=C4

-20°C

Ice Packs

Small Compound