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Molfinity

HDAC8-IN-1 - CAS 1417997-93-3

HDAC8-IN-1 - CAS 1417997-93-3

SKU:MF-0015488-01

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  • Bioactivity

    MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5) . HDAC8-IN-1 exhibits cytotoxicity against human lung CL1-5 cells without significant cytotoxicity for normal IMR-90 cells[1].

  • Target

    HDAC

  • Related Pathways

    DNA Damage/DNA Repair, Chromatin/Epigenetic

  • CAS Number

    1417901

  • Purity

    0.9983

  • Molecular Formula

    C22H19NO3

  • Molecular Weight

    345.39

  • SMILES

    COc1ccc(\C=C\C(=O)NO)c(c1)-c1ccc(cc1)-c1ccccc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound