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HER2-IN-14 - CAS 2414056-35-0

HER2-IN-14 - CAS 2414056-35-0

MF-0146859-01

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Product Details

  • Bioactivity

    HER2-IN-14 (Compound 34) is a potent HER2 inhibitor with an IC50 of 18 nM and demonstrates inhibitory activity against wild-type EGFR (wt-EGFR) with an IC50 of 6.3 μM [1].

  • Target

    EGFR, Others

  • Related Pathways

    Angiogenesis, Others, JAK/STAT signaling, Tyrosine Kinase/Adaptors

  • CAS Number

    2414021

  • Molecular Formula

    C26H23ClF2N8O3

  • Molecular Weight

    568.96

  • SMILES

    O(C=1C=2C(NC3=CC(Cl)=C(OC4=CC=5N(C=N4)N=CN5)C=C3)=NC=NC2C=CC1OC)[C@@H]6C(F)(F)CN(C)CC6

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound