Heteropodatoxin-2 - CAS 741730-12-1

Heteropodatoxin-2, a 30-amino acid peptide, inhibits the Kv4.2 current in Xenopus laevis oocytes through a voltage-dependent mechanism, exhibiting reduced blocking at more positive potentials [1].

Potassium Channel

Membrane transporter/Ion channel

741717

C144H207N39O46S6

3412.81

C(C=1C=2C(NC1)=CC=CC2)[C@H]3C(=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC=4C=5C(NC4)=CC=CC5)C(N)=O)=O)CC(O)=O)=O)CC(C)C)=O)CCCCN)=O)CSSCC6(C(=O)N[C@@]7(C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CC8=CC=C(O)C=C8)C(=O)N[C@@H]([C@@H](C)C)C(=O)N[C@](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N3)(CSSC[C@@](C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@]([C@@H](C)O)(C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N6)[H])(NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC9=CC=CC=C9)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)CC(O)=O)=O)CSSC7)[H])[H])[H])[H]

-20°C

Ice Packs

Peptide