Molfinity
HFI-142 - CAS 332164-34-8
HFI-142 - CAS 332164-34-8
SKU:MF-0013328-01
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Product Details
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Bioactivity
HFI-142 is a small-molecule inhibitor that binds specifically to the active site of aminopeptidase N and suppresses its enzymatic activity. HFI-142 has been demonstrated to inhibit leukotriene A4 biosynthesis in red blood cells, an effect that may offer therapeutic potential for the research in cancer by modulating inflammatory and metabolic pathways implicated in tumor growth and progression. HFI-142 was also shown to inhibit the activity of additional aminopeptidases, including aminopeptidase N, as well as other enzymes associated with protein metabolism.
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Target
Others, Aminopeptidase
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Related Pathways
Metabolism, Others
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CAS Number
332122
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Molecular Formula
C17H16N2O4
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Molecular Weight
312.32
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SMILES
O=C(OCC)C1=C(OC2=CC(O)=CC=C2C1C=3C=NC=CC3)N
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound