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Molfinity

HG-12-6 - CAS 2222354-57-4

HG-12-6 - CAS 2222354-57-4

MF-0022535-01

$2,436.80 USD
$2,436.80 USD
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Product Details

  • Bioactivity

    HG-12-6 is a type II inhibitor of IRAK4, demonstrating preferential binding to unphosphorylated inactive IRAK4 (IC50: 165 nM) and modulating IRAK4 activity in autoimmunity and inflammation.

  • Target

    Others, IRAK

  • Related Pathways

    Immunology/Inflammation, NF-κB, Others

  • CAS Number

    2222293

  • Molecular Formula

    C29H27F3N6O2S

  • Molecular Weight

    580.62

  • SMILES

    N(C(=O)C1CC1)C=2SC=3C(N2)=CC=C(N3)C4=CC(C(NC5=CC(C(F)(F)F)=C(CN6CCNCC6)C=C5)=O)=CC=C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound