Hibarimicin A - CAS 208588-76-5

Hibarimicin A is a tyrosine kinase inhibitor. It selectively inhibits the activity of src tyrosine kinase without affecting protein kinase A and C. Additionally, Hibarimicin A exhibits moderate activity against Gram-positive bacteria with a MIC ranging from 0.8 to 12.56 μg/mL.

Src, Antibacterial

Microbiology/Virology, Angiogenesis, Tyrosine Kinase/Adaptors

208588-76-5

C85H112O37

1725.78

C(CC)C12C3(O)C(C(O1)C=4C(C3=O)=C(O)C5=C(C4O)C(=O)C(OC)=C(C5=O)C6=C(OC)C(OC)=C7C(=C6O)C(O)=C8C(=C7)CC9C(O)(C8=O)C(CCC)(O)C(O[C@@H]%10O[C@H](C)[C@@H](O[C@@H]%11O[C@@H](C)[C@@](C(C)=O)(O)CC%11)CC%10)C(O)C9O[C@H]%12C[C@@H](O)[C@@H](O)[C@H](C)O%12)C(O[C@H]%13C[C@@H](O)[C@@H](O)[C@H](C)O%13)C(O)C2O[C@@H]%14O[C@H](C)[C@@H](O[C@H]%15O[C@@H](C)C(C(C)=O)(O)CC%15)CC%14

-20°C

Ice Packs

Natural Product