Himachalol - CAS 1891-45-8

Himachalol, a sesquiterpene, is an orally active compound with antispasmodic and anticancer properties found in cedarwood. It exhibits antiproliferative effects on melanoma cells and induces apoptosis (Apoptosis) by decreasing Bcl-2 levels and increasing Bax levels. Himachalol also causes systemic blood pressure reduction and peripheral vasodilation, and it inhibits carbamylcholine-induced intestinal spasms. In mice, the LD50 is 265 mg/kg (oral) and 247 mg/kg (intraperitoneal injection) .

Apoptosis, Bcl-2 Family

Apoptosis

1891-45-8

C15H26O

222.366

C[C@]1(O)[C@]2([C@](C=C(C)CC2)(C(C)(C)CCC1)[H])[H]

-20°C

Ice Packs

Natural Product