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Hippeastrine - CAS 477-17-8
Hippeastrine - CAS 477-17-8
SKU:MF-0155435-01
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Product Details
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Bioactivity
Hippeastrine is an active alkaloid that demonstrates a potent, dose-dependent inhibitory action against topoisomerase I (Top I), achieving an IC50 of 7.25 μg/mL. This compound also exhibits significant antiproliferative and anticancer activities [1].
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Target
Others, Topoisomerase
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Related Pathways
Others, DNA Damage/DNA Repair
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CAS Number
452
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Molecular Formula
C17H17NO5
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Molecular Weight
315.32
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SMILES
CN1[C@]2([C@@]3(C=4C(=CC5=C(C4)OCO5)C(=O)O[C@@]3([C@@H](O)C=C2CC1)[H])[H])[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product