Hirsutenone - CAS 41137-87-5

Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid peroxidation.Hirsutenone exhibits anti-cancer, and anti-filarial effects, it may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases through inhibition of ERK pathway-mediated NF-kappaB activation. Hirsutenone attenuates adipogenesis by directly targeting PI3K and ERK during MCE in 3T3-L1 preadipocytes, underscoring the potential therapeutic application of Hirsutenone in preventing obesity.

P53, PI3K, EGFR, Autophagy, Antifection, mTOR, ERK, IL Receptor, Akt, NF-κB

Cytoskeletal Signaling, Autophagy, Immunology/Inflammation, Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors, Microbiology/Virology, PI3K/Akt/mTOR signaling, NF-κB, JAK/STAT signaling, MAPK

41045

C19H20O5

328.36

Oc1ccc(CC\C=C\C(=O)CCc2ccc(O)c(O)c2)cc1O

-20°C

Ice Packs

Natural Product