HIV-1 inhibitor-21 - CAS 2554620-04-9

HIV-1 inhibitor-21 (compound 9b) is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase (RT) with an IC50 of 0.55 μM. It inhibits both wild-type HIV-1 (EC50: 12.7 nM) and mutant virus strain K103N (EC50: 10.4 nM), demonstrating relatively low cytotoxicity (CC50 for MT-4: 10.2 μM) .

HIV Protease, Others

Proteases/Proteasome, Others, Microbiology/Virology

2554620-04-9

C28H24N6O2

476.53

N(C=1C2=C(N=C(NC3=CC=C(C#N)C=C3)N1)C=C(OC)C(OC)=C2)C4=C(C)C=C(/C=C/C#N)C=C4C

-20°C

Ice Packs

Small Compound