HIV-1 inhibitor-57 - CAS 2745197-24-2

HIV-1 Inhibitor-57 (Compound 12g) is an antiviral agent that potently inhibits both wild-type and five common NNRTI-resistant strains of HIV-1, exhibiting EC50 values between 0.024 and 0.0010 μM. It achieves this efficacy by forming supplementary interactions with residues surrounding the binding site in the HIV-1 reverse transcriptase (RT) [1].

HIV Protease, Others

Microbiology/Virology, Others, Proteases/Proteasome

2745171

C25H24FN5O3S

493.55

FC1=C(C=CC(NC=2N=C(OC3=C(C)C=C(/C=C/C#N)C=C3C)C=CN2)=C1)N4CCS(=O)(=O)CC4

-20°C

Ice Packs

Small Compound