HIV-1 protease-IN-9 - CAS 2925381-27-5

HIV-1 protease-IN-9 (compound 5b), a potent HIV-1 protease inhibitor, exhibits strong antiviral efficacy with a dissociation constant (K_i) of 0.028 nM and a half-maximal inhibitory concentration (IC_50) of 66.8 nM [1].

HIV Protease

Microbiology/Virology, Proteases/Proteasome

2925349

C37H41N7O4S

679.83

N(C=1N=C(C=CN1)C=2C=CC=NC2)C3=CC(C(N[C@H]([C@@H](CN(S(=O)(=O)C4=CC=C(N)C=C4)CC(C)C)O)CC5=CC=CC=C5)=O)=CC=C3C

-20°C

Ice Packs

Small Compound