HJC0152 free base - CAS 1420290-88-5

HJC0152 (free base) is an orally active and potent STAT3 inhibitor that impedes cell cycle progression, induces apoptosis, and significantly reduces MDA-MB-231 xenograft tumor growth in mice [1].

STAT, Apoptosis

Stem Cells, JAK/STAT signaling, Apoptosis

1420197

C15H13Cl2N3O4

370.19

O=[N+](C(C=C1Cl)=CC=C1NC(C2=CC(Cl)=CC=C2OCCN)=O)[O-]

-20°C

Ice Packs

Small Compound