HKB99 - CAS 2414908-90-8

HKB99 is a mutant inhibitor of phosphoglycerate mutase 1 (PGAM1), which inhibits the growth and metastasis of non-small cell lung cancer.HKB99 acts synergistically with EGFR inhibitors and assists in the killing of tumors by EGFR inhibitors.HKB99 promotes oxidative stress, which induces alterations in a variety of signaling pathways.HKB99 can be used in the study of metabolism-related diseases.HKB99 can be used in the study of metabolism-related diseases.HKB99 can be used in the study of metabolism-related diseases.

ROS, Apoptosis, Phosphatase, Akt, ERK

MAPK, Metabolism, Apoptosis, Immunology/Inflammation, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling

2414810

0.9735

C23H18N2O6S

450.46

O=C1C=2C=CC=CC2C(=O)C3=C(O)C(O)=C(C=C13)NS(=O)(=O)C4=CC=C(C=C4)N5CCC5

-20°C

Ice Packs

Small Compound