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Molfinity

HL-8 - CAS 2766352-64-9

HL-8 - CAS 2766352-64-9

MF-0154635-01

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Product Details

  • Bioactivity

    HL-8, a PROTAC molecule, effectively targets and degrades PI3K kinase completely at a concentration of 10 μM within 8 hours, showcasing potential for cancer research [1].

  • Target

    PI3K, Others

  • Related Pathways

    PI3K/Akt/mTOR signaling, Others

  • CAS Number

    2766279

  • Molecular Formula

    C57H59F2N11O9S2

  • Molecular Weight

    1144.27

  • SMILES

    COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2ncc(-c3nnc(o3)-c3ccccc3C(=O)NCCCCCCC(=O)N[C@H](C(=O)N3C[C@@H](O)C[C@@H]3C(=O)NCc3ccc(cc3)-c3scnc3C)C(C)(C)C)n2c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound