HL2-m5 - CAS 2130846-15-8

HL2-m5 is an inhibitor of the sonic hedgehog/patched (Shh/PTCH1) interaction, with a Kd for Shh of 170 nM. It effectively inhibits the activation of the Hedgehog signaling pathway and the transcription of Gli-controlled genes, with an IC50 of 230 nM.

Hedgehog/Smoothened

GPCR/G Protein, Stem Cells

2130846-15-8

C70H101N15O24S3

1632.83

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