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HM5023507 - CAS 1549740-86-4
HM5023507 - CAS 1549740-86-4
SKU:MF-0144843-01
Regular price
$1,910.30 USD
Regular price
Sale price
$1,910.30 USD
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Product Details
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Bioactivity
HM5023507, an orally active dual inhibitor of δγ isoforms in immune signaling. HM5023507 inhibited PI3Kδ and PI3Kγ isoforms with greater than 100-fold selectivity against PI3Kα and PI3Kβ in recombinant enzymatic assays and in primary human immune cells with an exquisite selectivity against other targets.
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Target
Others
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Related Pathways
Others
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CAS Number
1549650
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Molecular Formula
C21H18ClN7O2
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Molecular Weight
435.87
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SMILES
O=C1N(C(=NN2C1=C(Cl)C=C2)[C@@H]3N(CC3)C=4C(C(C)=O)=CN=C(N)N4)C5=CC=CC=C5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound