HMG499 - CAS 2416941-68-7

HMG499 is a potent and selective HMG-CoA reductase inhibitor with an IC50 of 0.41 μM, capable of eliminating statins-induced accumulation of HMGCR, lowering serum cholesterol levels, and decreasing atherosclerosis [1].

Autophagy, HMG-CoA Reductase

Autophagy, Metabolism

2416866

C33H54O3

498.78

C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(CC=C)(CC=C)O)C)(CC4)[H])[H])([C@@H](O)C=C1C(C)(C)[C@@H](O)CC2)[H])[H]

-20°C

Ice Packs

Small Compound