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HMS607P03 - CAS 361198-09-6
HMS607P03 - CAS 361198-09-6
SKU:MF-0144011-01
Regular price
$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
HMS607P03 is an activator of SIRT1 which induces autophagic cell death via the AMPK-mTOR-ULK complex and induces mitophagy by the SIRT1-PINK1-Parkin pathway. HMS607P03 downregulates 14-3-3γ, catalase, profilin-1, and HSP90α.
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Target
Others, Sirtuin
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Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic, Others
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CAS Number
361198-09-6
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Molecular Formula
C26H19ClN4O3S2
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Molecular Weight
535.04
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SMILES
O=C1N(C2=NC=3C(S2)=CC=CC3)N=C(CSC4=CC=C(Cl)C=C4)C1=CNCC=5C=C6C(=CC5)OCO6
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound