HNC-1664 - CAS 2127358-36-3

HNC-1664 is an orally active inhibitor of RNA-dependent RNA polymerase (RdRP) . It exhibits broad-spectrum antiviral activity against coronaviruses, including SARS-CoV-2 wild type and its variants (XBB.1.18, HK.3.1, BF.7.14, BA.1, HCoV-229E, HCoV-OC43), as well as arenaviruses. HNC-1664 also demonstrates anti-infective efficacy in a mouse model infected with the SARS-CoV-2 Delta variant.

Anti-infection, SARS-CoV, DNA/RNA Synthesis, Virus Protease

Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Microbiology/Virology

2127319

C12H13FIN3O3

393.153

F[C@@H]1[C@H](N2C=3C(C(I)=C2)=C(C)N=CN3)O[C@H](CO)[C@H]1O

-20°C

Ice Packs

Small Compound