HnRNPK-IN-1 - CAS 2313528-04-8

HnRNPK-IN-1 is a specific ligand that binds to the heterogeneous nuclear ribonucleoprotein K (hnRNPK) with high affinity, evidenced by Kd values of 4.6 μM and 2.6 μM determined using surface plasmon resonance (SPR) and microscale thermophoresis (MST), respectively. This binding event leads to the disruption of hnRNPK's interaction with the c-myc promoter, resulting in the inhibition of c-myc transcription. Additionally, hnRNPK-IN-1 induces apoptosis in Hela cells and exhibits potent anti-tumor activities[1].

Others, c-Myc, Apoptosis

Others, Apoptosis, Cell Cycle/Checkpoint

2313528-04-8

C23H21N3O5

419.43

COc1ccc(cc1)C(=O)\C=C\c1cc(N2CCOCC2)c2cc(ccc2n1)[N+]([O-])=O

-20°C

Ice Packs

Small Compound