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Homocarbonyltopsentin - CAS 172286-77-0
Homocarbonyltopsentin - CAS 172286-77-0
SKU:MF-0031637-01
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Product Details
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Bioactivity
Homocarbonyltopsentin is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing (EC50: 16 μM) .
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Target
Others, DNA/RNA Synthesis
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Related Pathways
Others, DNA Damage/DNA Repair, Cell Cycle/Checkpoint
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CAS Number
172209
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Molecular Formula
C21H14N4O3
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Molecular Weight
370.36
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SMILES
Oc1ccc2c(c[nH]c2c1)C(=O)c1ncc([nH]1)C(=O)c1c[nH]c2ccccc12
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound