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Molfinity

Homocarbonyltopsentin - CAS 172286-77-0

Homocarbonyltopsentin - CAS 172286-77-0

SKU:MF-0031637-01

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  • Bioactivity

    Homocarbonyltopsentin is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing (EC50: 16 μM) .

  • Target

    Others, DNA/RNA Synthesis

  • Related Pathways

    Others, DNA Damage/DNA Repair, Cell Cycle/Checkpoint

  • CAS Number

    172209

  • Molecular Formula

    C21H14N4O3

  • Molecular Weight

    370.36

  • SMILES

    Oc1ccc2c(c[nH]c2c1)C(=O)c1ncc([nH]1)C(=O)c1c[nH]c2ccccc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound