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Molfinity

HPK1-IN-33 - CAS 2920000-86-6

HPK1-IN-33 - CAS 2920000-86-6

MF-0146555-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    HPK1-IN-33 (compound 21), a Hematopoietic Progenitor Kinase 1 (HPK1) inhibitor, exhibits a high potency with a K_i of 1.7 nM. It effectively inhibits IL-2 production, demonstrating EC_50 values of 286 nM in Jurkat WT cells and >10000 nM in Jurkat HPK1 KO cells [1].

  • Target

    Others, MAPK

  • Related Pathways

    Others, MAPK

  • CAS Number

    2919908

  • Molecular Formula

    C18H16ClFN6

  • Molecular Weight

    370.81

  • SMILES

    N#Cc1cccc(-c2c(Cl)[nH]c3ncnc(N4CC[C@@H](F)[C@@H](N)C4)c23)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound