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Molfinity

HQ461 - CAS 1226443-41-9

HQ461 - CAS 1226443-41-9

MF-0019587-01

$38.41 USD
$38.41 USD
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Product Details

  • Bioactivity

    HQ461 is a molecular glue that promotes CDK12-DDB1 interaction, triggering cyclin K degradation, decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death.

  • Target

    Molecular Glues, CDK

  • Related Pathways

    PROTAC, Cell Cycle/Checkpoint

  • CAS Number

    1226393

  • Purity

    0.9811

  • Molecular Formula

    C15H15N5OS2

  • Molecular Weight

    345.44

  • SMILES

    Cc1cnc(NC(=O)Cc2csc(Nc3cccc(C)n3)n2)s1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC