HR68 - CAS 2454582-64-8

HR68, a derivative of the peroxisome proliferator-activated receptor (PPAR) agonist fenofibric acid, serves as an anticancer agent. It effectively reduces the viability of LN-229 glioblastoma cells, with an IC50 value of 1.17 μM. Notably, HR68 is capable of crossing the blood-brain barrier in temozolomide-resistant orthotopic patient-derived xenograft (PDX) mouse models of glioblastoma.

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Others

2454582-64-8

C22H19ClN2O3

394.85

CC(C(NC1=CC=NC=C1)=O)(OC2=CC=C(C(C3=CC=C(C=C3)Cl)=O)C=C2)C

-20°C

Ice Packs

Small Compound