HS-276 - CAS 2767422-72-8

HS-276 is a highly selective, orally active inhibitor of TAK1 (Ki: 2.5 nM) . HS-276 significantly inhibits TAK1 (IC50: 8.25 nM), CLK2 (IC50: 29 nM), GCK (IC50: 22 nM), ULK2 (IC50: 63 nM), MAP4K5 (IC50. HS-276 can be used to study rheumatoid arthritis (RA) .

IRAK, Casein Kinase, MAPK, TNF

Stem Cells, Metabolism, Apoptosis, NF-κB, Immunology/Inflammation, MAPK

2767342

0.9881

C24H29N5O2

419.52

C(CC)N1C=2C(N=C1NC(=O)C3=CC(C(N)=O)=CC=C3)=CC=C(CN4CCCCC4)C2

-20°C

Ice Packs

Small Compound