HS-345 - CAS 1462329-41-4

HS-345, a TrkA/Akt inhibitor, exhibits potent anti-pancreatic cancer properties. This compound inhibits the growth and proliferation of pancreatic cancer cells by blocking the TrkA/Akt signaling pathway and induces cell apoptosis (Apoptosis) . Additionally, HS-345 inhibits angiogenesis by reducing the expression of HIF-1α and VEGF. It holds promise for use in pancreatic cancer research.

Akt, Trk receptor

Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Tyrosine Kinase/Adaptors

1462284

C19H18N6O2S

394.45

O=S(=O)(C=1C=C(C=NC1N)C2=CN=C3NC=C(C=4C=CN=CC4)C3=C2)N(C)C

-20°C

Ice Packs

Small Compound