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Molfinity

HS148 - CAS 1892595-16-2

HS148 - CAS 1892595-16-2

MF-0099528-01

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Product Details

  • Bioactivity

    HS148 is a selective inhibitor of DAPK3 (death-associated protein kinase 3), with a Ki value of 119 nM. Inhibition of DAPK3 by HS148 has been shown to reduce the progression of gastric cancer by activating the ULK1-dependent pathway, which is implicated in cellular autophagy and tumor suppression mechanisms.

  • Target

    DAPK

  • Related Pathways

    Apoptosis

  • CAS Number

    1892577

  • Purity

    0.98024

  • Molecular Formula

    C15H14FN5O2S

  • Molecular Weight

    347.37

  • SMILES

    O=C1N=C(SC(C(=O)N)CC)NC2=C1C=NN2C=3C=CC=C(F)C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound