HSD17B13-IN-1 - CAS 2770246-02-9

HSD17B13-IN-1 (compound 2) acts as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 value of <0.1 μM with estradiol as a substrate. It plays a crucial role in addressing nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].

Dehydrogenase

Metabolism

2770246-02-9

C23H14Cl2F3N3O4

524.28

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=C(OC(F)(F)F)C=CC=C4)C3=O)=CC=C2

-20°C

Ice Packs

Small Compound