HSD17B13-IN-105 - CAS 3012624-88-0

HSD17B13-IN-105 (Compound EX.87) is a selective inhibitor of 17β-hydroxysteroid dehydrogenase 13 (17BHSD13) with an IC50 value of 0.036 μM, demonstrating high selectivity over 17BHSD4, which has an IC50 value of 31.5 μM. HSD17B13-IN-105 shows potential for research in liver diseases such as non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) .

Dehydrogenase

Metabolism

3012536

C15H14F3N3O4

357.29

FC1=C(C2=NC(C(=O)N3C[C@@H](C)O[C@@H](C)C3)=NO2)C=C(F)C(F)=C1O

-20°C

Ice Packs

Small Compound