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Molfinity

HSD17B13-IN-11 - CAS 2758802-03-6

HSD17B13-IN-11 - CAS 2758802-03-6

SKU:MF-0120713-01

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  • Bioactivity

    HSD17B13-IN-11 (Compound 2), with IC50 values of ≤ 1 μM for leukotriene B3 and ≤ 0.1 μM for estradiol, effectively inhibits hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) . This compound is utilized in studying various medical conditions including liver diseases, metabolic and cardiovascular disorders, particularly non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI) [1].

  • Target

    Dehydrogenase

  • Related Pathways

    Metabolism

  • CAS Number

    2758802-03-6

  • Molecular Formula

    C16H17ClN2O3S

  • Molecular Weight

    352.84

  • SMILES

    C(NCC(C)C)(=O)C1=C(NC(=O)C2=CC(Cl)=C(O)C=C2)C=CS1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound