HSD17B13-IN-14 - CAS 2758802-05-8

HSD17B13-IN-14 (Compound 4) acts as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), achieving an IC 50 of ≤ 1 μM for leukotriene B3 and ≤ 0.1 μM for estradiol. This compound is utilized in studying various conditions, including liver diseases, metabolic disorders, and cardiovascular diseases like NAFLD or NASH, as well as drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2758802-05-8

C21H16ClN3O3S

425.89

C(NC(=O)C1=C(NC(=O)C2=CC(Cl)=C(O)C=C2)C=CS1)C=3C=4C(NC3)=CC=CC4

-20°C

Ice Packs

Small Compound