HSD17B13-IN-15 - CAS 2758802-07-0

HSD17B13-IN-15 (Compound 6) acts as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting IC 50 values of ≤ 1 μM for leukotriene B3 and ≤ 0.1 μM for estradiol. This compound finds applications in studying various conditions, including liver diseases, metabolic disorders, and cardiovascular diseases such as NAFLD, NASH, or drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2758802-07-0

C21H17ClN2O4S

428.89

C(NC1CC=2C(OC1)=CC=CC2)(=O)C3=C(NC(=O)C4=CC(Cl)=C(O)C=C4)C=CS3

-20°C

Ice Packs

Small Compound