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Molfinity

HSD17B13-IN-18 - CAS 2758802-14-9

HSD17B13-IN-18 - CAS 2758802-14-9

MF-0120720-01

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Product Details

  • Bioactivity

    HSD17B13-IN-18 (compound 13) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting IC50 values of < 0.1 μM for estradiol and < 1 μM for Leukotriene B3 as substrates. This compound is crucial in managing nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].

  • Target

    Dehydrogenase

  • Related Pathways

    Metabolism

  • CAS Number

    2758802-14-9

  • Molecular Formula

    C21H19ClN2O4S

  • Molecular Weight

    430.9

  • SMILES

    C(NCCC1=C(OC)C=CC=C1)(=O)C2=C(NC(=O)C3=CC(Cl)=C(O)C=C3)SC=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound