HSD17B13-IN-19 - CAS 2758802-17-2

HSD17B13-IN-19 (compound 16) acts as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting IC50 values under 0.1 μM and under 1 μM when using estradiol and Leukotriene B3 as substrates, respectively. This compound is crucial in the treatment of nonalcoholic fatty liver diseases (NAFLDs), such as nonalcoholic steatohepatitis (NASH) [1].

Dehydrogenase

Metabolism

2758802-17-2

C23H23FN2O4S

442.5

N(C(=O)C1=CC(F)=C(O)C=C1)C2=C(C(NCCC3=C(OC)C=CC=C3)=O)C(C)=C(C)S2

-20°C

Ice Packs

Small Compound