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Molfinity

HSD17B13-IN-23 - CAS 2758802-19-4

HSD17B13-IN-23 - CAS 2758802-19-4

MF-0120724-01

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Product Details

  • Bioactivity

    HSD17B13-IN-23 (compound 18) serves as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating inhibition constants (IC 50) of <0.1 μM and <1 μM when estradiol and Leukotriene B3 act as substrates, respectively. This compound is significant in the management of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].

  • Target

    Dehydrogenase

  • Related Pathways

    Metabolism

  • CAS Number

    2758802-19-4

  • Molecular Formula

    C18H20F2N2O3S

  • Molecular Weight

    382.42

  • SMILES

    C(NCCC(C)(C)C)(=O)C1=C(NC(=O)C2=CC(F)=C(O)C(F)=C2)C=CS1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound